| 名稱 | Recombinant Human IL-6 |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | 重組IL - 6是一種多效性的細胞因子在宿主防御中起著重要的作用,調節(jié)免疫和炎癥反應。產生的T細胞,單核細胞、成纖維細胞、內皮細胞和角化細胞,il - 6不同的生物功能。刺激b細胞分化和產生抗體,synergizes IL-3巨核細胞發(fā)展生產和血小板,誘發(fā)肝acute-phase蛋白質的表達,調節(jié)骨代謝。il - 6通過il - 6受體信號系統,包括兩個鏈,IL-6Rαgp130。} |
產品展示 / PRODUCTS
- 詳細內容
一.產品名稱：Recombinant Human IL-6/重組IL-6
二.Catalog Number:AF-200-06
三.Synonyms:26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
四.Description:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and plaet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Manufactured using all non-animal reagents.
五.AA Sequence:
PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
九.Cross Reactivity:Monkey, Mouse, Rat, Human
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區(qū)廂黃旗2號樓1層4-179室